Based on over 80 recent clinical and epidemiological Studies with more than 10000 participants,  elevated blood levels of homocysteine  have been linked to increased risk of premature coronary artery disease, stroke, and thromboembolism.

Abnormal homocysteine levels appear to contribute to atherosclerosis in at least three ways: (1) a direct toxic effect that damages the cells lining the inside of the arteries, (2) interference with clotting factors, and (3) oxidation of low-density lipoproteins (LDL).

Pharmacological doses of Folic Acid ( in combination or not with B12, B6 vitamins ) , for a period of 4 weeks, decrease drastically the Homocysteine levels.

Administration of Folic Acid can be a safe and inexpensive preventive or therapeutic treatment for the reduction of homocysteine levels.